Association of Clinical Scientists

Introduction

The 130th Meeting of the Association of Clinical Scientists will be held in San Antonio, Texas, from Wednesday, 12 May, to Sunday, 16 May 2010. The headquarters will be the Historic Wyndham St. Anthony Hotel, located in downtown San Antonio, a few steps from the famous River Walk. The meeting will be hosted by the University of Texas Health Science Center-San Antonio. Drs. Robert L. Reddick and Robert L. Hunter, Jr., Co-Chairs of the Program Committee, cordially invite you to attend.

Scientific Session Topics

• Transfusion Medicine and Hematology
• Molecular Biology and Oncology
• Atherosclerosis
• Cell and Tissue Pathology
• Therapeutics and Toxicology
• Informatics and Clinical Biochemistry
• Clinical Science in Practice
• Clinical Microbiology and Immunology
• Tutorial in Surgical Pathology

General Schedule

The meeting registration desk will be open and committee meetings will be held at the St. Anthony Hotel on Wednesday afternoon and evening. Scientific sessions will be held at the hotel on Thursday and Saturday. The Friday morning session will be at the University of Texas Health Science Center.

Program

Wednesday, 12 May 2010
2:00 pm	Meeting registration desk opens (Hotel lobby)
2:30 pm	CME Committee meeting
3:30 pm	Executive Committee meeting
5:00 pm	Editorial Board meeting
7:45 pm	Executive Committee meeting with Past-Presidents, Regional Delegates, and Chairs of Sections and Committees

Thursday, 13 May 2010
Session A: Transfusion Medicine (Chairs: Robert L. Hunter & Megali J. Fontaine)
8:00 am	Welcome. Charles D. Hawker, President of the Association; Robert L. Hunter and Robert L. Reddick, Co-chairs of the Program Committee
8:05 am	[1] Blood centers and their responsibility for donor well-being. Robert F. Reiss, New York, NY
8:30 am	[2] Current controversy regarding the storage age of red blood cell units and clinical outcomes. Nicholas Bandarenko III, Durham, NC
9:00 am	[3] Allogenic blood transfusion: why do we care? James R. Stubbs, Rochester, MN
9:30 am	[4] Algorithmic and consultative integration of transfusion medicine and blood coagulation. Robert E. Brown et al., Houston, TX
10:00 am	[5] Predicting platelet flow cytometric crossmatch compatibility by HLA antibody median fluorescence intensity. Amanda Wehler et al., Hershey, PA
10:15 am	Refreshments
Session B: Hematology (Chairs: Jonathan S. Krauss & Robert F. Reiss)
10:30 am	[6] Acquired von Willebrand disease: laboratory diagnosis and therapy. John Lazarchick, Charleston, SC
11:00 am	[7] Transfusion-related alloantibodies in sickle cell disease. Jonathan S. Krauss, Augusta, GA
11:30 am	[8] Utility and limitations of thromboelasto-graphy in the management of coagulation disorders. Jun Teruya, Houston, TX
11:45 am	[9] Activated protein C resistance screening prior to testing for factor V Leiden mutation. Frederick L. Kiechle et al., Hollywood, FL
noon	Luncheon recess
Luncheon Sponsored by the Section on Hematology & Transfusion Medicine (Chair: John Lazarchick)
12:05 pm	[10] Case studies in transfusion medicine and therapeutic apheresis. Fouad N. Boctor, Manhasset, NY, and Myra L. Wilkerson, Danville, PA
Session C: Molecular Biology & Genetics (Chairs: Frederick L. Kiechle & James R. Stubbs)
1:30 pm	[11] Using small pool PCR to detect microsatellite instability in saliva cells. Peter C. Hu, Houston, TX
2:00 pm	[12] Abnormal hormetic morphogen gradient signaling in the etiology of cancer. Egil Fosslien, Chicago, IL
2:30 pm	[13] Glycan expression profile in freshly isolated pancreatic islets. Magali J. Fontaine et al., Stanford, CA
3:00 pm	[14] The pathology and genetics of metachondromatosis. Kyle Kurek et al., Boston, MA
3:15 pm	Refreshments
Session D: Oncology & Proteomics (Chairs: M. Kent Froberg & Joseph C Parker, Jr.)
3:30 pm	[15] Integration of array-based karyotyping in the management of oncology patients. Shelly R. Gunn, San Antonio, TX
4:00 pm	[16] Array-based comparative genomic hybridization in chronic lymphocytic leukemia. P. Alan Lennon, Houston, TX
4:30 pm	[17] Molecular events of cholangio-carcinogenesis. Consolato M. Sergi, Edmonton, Alberta, Canada
5:00 pm	[18] Morphoproteomics guides targeted combinatorial therapy for metastatic renal cell carcinoma. Jamie Buryanek et al., Houston, TX
5:15 pm	[19] Salinomycin: genomic and antitumoral effects in neuroblastoma. Priya Weerasinghe and Robert E. Brown, Houston, TX
5:30 pm	[20] Immunochemical detection of epithelial-mesenchymal transition and properties of stem cells in anaplastic thyroid carcinoma. Jing Liu and Robert E. Brown, Houston, TX
5:45 pm	[21] Impacts of hypoxia inducible factor 1-alpha and hepatitis virus X on the proliferation of hepatocytes. George G. Chen, Hong Kong, China
6:00 pm	Adjournment The evening is free for participants to stroll and dine on San Antonio's famous Riverwalk, which is a few steps from the St. Anthony Hotel.
7:30 pm	Musicale Rehearsal (Myra L. Wilkerson, Chair for the Committee on Music and Arts)
7:45 pm	Awards Committee Meeting (Frederick Muschenheim, Chair)
8:30 pm	Nominating Committee Meeting (M. Kent Froberg, Chair)

Friday, 14 May 2010
(Bus leaves Hotel at 7:20 am to the University of Texas Health Sciences Center-San Antonio
Session E: Atherosclerosis (Chairs: Joseph A. Knight & Egil Fosslien)
8:15 am	[22] Abraham J. Gitlitz Memorial Lecture: Lipoproteins, infection, homocysteine, and the vulnerable plaque. Kilmer S. McCully, Boston, MA, and Uffe Ravnskov, Lund, Sweden
9:15 am	[23] Mouse models of atherosclerosis: the apo-E story. Robert L. Reddick, San Antonio, TX
9:45 am	[24] Thio-oxidative stress, macrophage recruitment, and atherosclerosis. Reto Asmis, San Antonio, TX
10:15 am	[25] Quantification of plaque volume by micro-CT techniques. Seema Ahuja, San Antonio, TX
10:30 am	[26] Is cytomegalovirus associated with coronary artery stenosis in younger patients? M Kent Froberg, Virginia, MN
10:45 am	Refreshments
Session F: Tour of Clinical Laboratories
11:00 am	[27] Innovations in Clinical Laboratory Services at the University of Texas Health Science Center-San Antonio. Robert L. Reddick et al., San Antonio, TX
noon	Bus returns to Hotel
1:30 pm	Bus Excursion: A special tour of San Antonio and environs for participants and accompanying persons (Bus will return to the hotel at 6:00 pm)
Annual Reception and Banquet (St. Anthony Hotel, 7:00 pm) Toastmaster: Charles D. Hawker, President
Young Clinical Scientist Awards, presented by Frederick Muschenheim to Consolato M. Sergi, Edmonton, Alberta, Canada, and L. Brannon Thomas, Tampa, FL Diploma of Honor, presented by Robert E. Brown to M. Kent Froberg, Virginia, MN Clinical Scientist of the Year Award, presented by Peter Farmer to Joseph A. Knight, Salt Lake City, UT Banquet Address: Life in Texas in 1833, Carl Hacker, Houston, TX

Saturday, 15 May 2010
6:30 am	Run for the Lilies (2 miles), (Organized by Filiberto Cavazos, Chair, Athletics Committee)
7:00 am	Breakfast Meeting of the Membership and Credentials Committees (Dani S. Zander and Vincent A. DeBari, Chairs)
Session G: Surgical Pathology Tutorial (Session G is concurrent with Session J) (Dani S. Zander & Nina Tatevian, Chairs)
8:00 am	[28] Tutorial on unusual and misplaced lesions of the upper and lower respiratory tract. Jaishree Jagirdar, with presentations by Steven Held, Kenneth Holder, William McClain, and Taylor Hartley, San Antonio, TX
10:00 am	Refreshments
Session J: Therapeutics & Toxicology (Session J is concurrent with Session G) (Donald Forman & George B. Kudolo, Chairs)
8:00 am	[41] When things go wrong with properly prescribed medicines: lessons from postmortem forensic toxicology. George B. Kudolo, San Antonio, TX
8:15 am	[42] Pharmacogenomics of ethanol, nicotine, and codeine. Wieslaw Furmaga, San Antonio, TX
8:30 am	[43] Toxic effects of herbal medicines. Amitava Dasgupta, Houston, TX
8:45 am	[44] Prescription drugs and human performance impairment. Ashraf Mozayani et al., Houston, TX
9:00 am	[45] Monitoring compliance in patients with chronic pain requires lower drug cut-offs and more specific assays. Amadeo Pesce et al., San Diego, CA
9:15 am	[46] Alcohol abuse, an evolutionary metabolic syndrome. Joseph C. Parker, Jr., Louisville, KY
9:45 am	Refreshments
Session H: Cell & Tissue Pathology (Session H is concurrent with Session K) (Peter Farmer & Juliana Szakacs, Chairs)
10:15 am	[29] Non-melanoma skin cancer: grading and staging. Manjunath S. Vadmal and Payam Saadat, Los Angeles, CA
10:45 am	[30] Cutaneous basaloid neoplasms. L. Brannon Thomas et al., Tampa, FL
11:15 am	[31] Nonalcoholic steatohepatitis in children. Nina Tatevian et al., Houston, TX
11:45 am	[32] Beta-catenin expression in benign and malignant pleural disorders. Waseem Q. Anani et al., Hershey, PA
noon	[33] Non-uremic calciphylaxis in a patient with autoimmune myelofibrosis. Manjunath S. Vadmal and Payam Saadat, Los Angeles, CA
12:15 pm	Luncheon recess
Session K: Clinical Informatics & Clinical Biochemistry (Session K is concurrent with Session H) (Sidney M. Hopfer & John Savory, Chairs)
10:00 am	[47] The emergence of computer technology in clinical pathology and its vital role in reducing costs and improving patient care. John Savory, Charlottesville, VA
10:30 am	[48] Use of a novel camera system and optical character verification to identify mislabeled specimens. Charles D. Hawker, Salt Lake City, UT
10:45 am	[49] Measuring crosstalk ratios in biological pathways. Mary F. McGuire et al., Houston, TX
11:00 am	[50] Variation in urinary myoinositol in renal disorders. Barry I Freedman and Zak K. Shihabi, Winston-Salem, NC
11:15 am	[51] Workshop on quantitative real-time PCR. P. Alan Lennon, Houston, TX
12:15 pm	Luncheon Recess
Luncheon Sponsored by the Section on Clinical Science in Practice (Frederick Muschenheim, Chair)
12:20 pm	[34] The clinical laboratory in the future of personalized healthcare. Roland Valdes Jr., Louisville, KY
Session I: Frontiers of Clinical Science (Session I is concurrent with Session L) (Robert E. Brown & Manjunath S. Vadmal, Chairs)
1:45 pm	[35] Workshop on multispectral imaging: revolutionary instrumentation for anatomic pathology. Robert C. Hunter and Robert E. Brown, Houston, TX
2:45 pm	[36] Touchscreen procedure templates in the surgical pathology gross laboratory. Joseph A. DelTondo et al., Hershey, PA
3:00 pm	[37] Experiential learning in quality improvement education for residents. Dani S. Zander et al., Hershey, PA
3:15 pm	[38] Implementation of cancer protocols: standardization and acceptance. Philip Foulis and Leah Strickland-Marmol, Tampa, FL
3:30 pm	[39] Evidence-based practice in clinical laboratory science. Elizabeth Kenimer Leibach, Augusta, GA
3:45 pm	[40] Optimization of C4d for automated immunohistochemistry on formalin-fixed paraffin-embedded tissue. Atif Ahmed et al., Kansas City, MO
4:00 pm	Refreshments
Session L: Clinical Science in Practice (Session L is concurrent with Session I) (Raymond W. Ryan & Vincent A. DeBari, Chairs)
1:45 pm	[52] Zygomycosis in immunocompromised individuals. Annette W. Fothergill, San Antonio, TX.
2:15 pm	[53] Methicillin-resistant Staphylococcus aureus (MRSA) screening at Memorial Healthcare System in South Florida. Frederick L Kiechle and Rodney C. Arcenas, Hollywood, FL
2:30 pm	[54] Epidemiology and vancomycin susceptibility of MRSA at Hershey Medical Center. Klaudia Kosowska-Shick et al., Hershey, PA
2:45 pm	[55] Biomarkers for prolonged QT interval syndrome in HIV-infected subjects. H Shaaban et al, Newark, NJ
3:00 pm	[56] Association of hypophosphatemia with failure to wean from mechanical ventilation. Mohammed Alsumarain et al., Newark, NJ
3:15 pm	[57] Medical contributions of the surged vitamin D test. Pai C. Kao, Rochester, MN
3:45 pm	[58] Vitamin D: wonder drug or just hype? Clive Hamlin, Cleveland, OH
4:00 pm	Refreshments
4:15 pm	Business Meeting of the Association, Charles D. Hawker, President
5:30 pm	Adjournment
Association Musicale and Art Show (St. Anthony Hotel; 7:30 pm) with wine and cheese reception during intermission. Organized by Myra L. Wilkerson for the Committee on Music and Fine Arts

Abstract Instructions

Abstract Submission Deadline has passed and abstracts cannot be submitted for the 2010 meeting.

Association members and guests are invited to present papers on their research. Each proffered paper will have 12 minutes for oral delivery and 3 min for discussion. The deadline for receipt of abstracts is Friday, 15 January 2010. The Abstract Submission Instructions and the required CAP Full Disclosure Form are below. Please note the CAP Full Disclosure Form must be completed by the presenting author and each co-author. The Full Disclosure Forms are required for CME accreditation by the College of American Pathologists (CAP). The abstracts will be published in the Program and the Annals of Clinical & Laboratory Science.

• Abstract Submission Instructions
• CAP Full Disclosure Form

Continuing Education (CME and CE)

CME information for the 2010 meeting will be posted at a later date. The 2009 meeting of the Association provided 20.25 AMA PRA Category 1 Credits™ from the College of American Pathologists.

Registration

The regular registration fee is $395. Junior members, emeritus members, and non-member residents or post-doctoral fellows may pay a reduced fee ($295). The registration fee includes one ticket to the reception and banquet on Friday evening. Tickets for the luncheons of scientific sections cost $30. Admission to the musicale and art show on Saturday evening is free. Please download the meeting registration form, fill it out, and send it to the Secretary-Treasurer by fax or regular mail.

Accommodations & Transportation

Hotel Accommodations

The St. Anthony Hotel, rated Four Diamonds by AAA, has 352 guest rooms and splendid conference facilities. The special convention rate will be $169/room (single or double) plus taxes. Currently, the tax rate is 16.75%. The famous Peacock Alley Lobby of the St. Anthony Hotel is one of San Antonio’s landmarks. The hotel’s amenities include a roof-top swimming pool, a fitness center, and a business center. The hotel’s address is 300 East Travis, San Antonio, TX 78205, and its website is www.thestanthonyhotel.com. The number of available rooms at the convention rate is limited, so you should make your reservations early by calling the hotel at (210) 354-9235, (210) 227-4392, or by sending a fax to (210) 222-1896. Please specify that you will attend the Association’s meeting. The cut-off date for reservations at the special convention rate is 12 April 2010.

Transportation

Travel time between the St. Anthony Hotel and San Antonio International Airport is 15 minutes. Shuttle service costs $18 one-way and taxi service averages $23 for one to four passengers. Guest parking with in/out privileges at the hotel costs $17/night (self-parking) or $23 (valet parking).

Future Meetings

2011

(May 18 - 22) Louisville, Kentucky, at the historic Seelbach Hilton Louisville Hotel, only 7 miles from the Louisville Airport, hosted by the University of Louisville School of Medicine. Drs. Joseph C. Parker and Roland Valdes, Jr., Co Chairs, have announced a meeting theme of Personalized Medicine and Genomics.

2012

(May 23 - 26) Mobile, Alabama, at the Renaissance Mobile Riverview Plaza Hotel, 14 miles from the Mobile Airport, hosted by the University of South Alabama School of Medicine. Dr. J. Allan Tucker will be the Meeting Chairperson.