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Introduction

The 133rd Meeting of the Association of Clinical Scientists will be held in Boston, Massachusetts on May 22 to 25, 2013. The headquarters will be the Omni Parker House Hotel, located in downtown Boston. The meeting will be hosted by the Harvard Vanguard Medical Associates. Dr. Juliana Szakacs, Chair of the Program Committee, cordially invites you to attend this outstanding conference. The program theme will be Advances in Molecular / Genetic Diagnostics and Pediatric Pathology.

Kyle C. Kurek, MD, will deliver the Claude P. Brown Memorial Lecture on “Cartilage Tumor Syndromes – Genetic  Discovery to New Tumor Paradigms.”

The Association’s annual awards will also be presented. As announced by the Awards Committee during the Annual Business Meeting in Mobile, the 2013 awards are:

John Savory, PhD, Charlottesville, VA – Gold Headed Cane
Clive R. Hamlin, PhD, Cleveland, OH – Clinical Scientist of the Year
Vincent A. DeBari, PhD, South Orange, NJ – Diploma of Honor
Lori Millner, PhD, Louisville, KY – Young Clinical Scientist, Innovation and Science
Frederick Strathmann, PhD, Salt Lake City, UT – Young Clinical Scientist, Technology Development
Joshua Bornhorst, PhD, Little Rock, AR – Young Clinical Scientist, Clinical Applications
Kristine Konopka, MD, Houston, TX – Young Clinical Scientist, Clinical Applications

Program

Wednesday, 22 May

(Omni Parker House Hotel)

2:00 pm    Meeting registration desk opens (lobby)
2:30 pm    Educational Accreditation Committee meeting (Gardner Room)
3:30 pm    Executive Committee meeting (Gardner Room)
5:30 pm    Editorial Board reception (Stowe Room)

Thursday, 23 May

(Omni Parker House Hotel) Kennedy Room

Session A
Advances in Molecular & Genetic Diagnostics
Chairs: Roland Valdes, Jr., & Juliana Szakacs

7:45 am    Welcome. Roland Valdes Jr., President of the Association; Juliana G Szakacs and Kyle Kurek, Co-chairs of Program Committee
8:00 am    [1] Claude P. Brown Memorial Lecture: Cartilage Tumor Syndromes- Genetic Discovery to New Tumor Paradigms. Kyle Kurek, Boston, MA
8:30 am    [2] Individualizing Genetic Testing Decisions in a Large Multi-Specialty Group Practice. Susan Pauker, Boston, MA
8:45 am    [3] Mapping the Undiscovered Country: Counsyl’s 100,000 Pan-Ethnic Clinical Screens. Eric A. Evans, Stanford, CA
9:00 am    [4] Boston Children’s Hospital Whole Genome Sequencing Pilot Project. David T. Miller, Boston, MA
9:15 am    [5] Chromosomal Microarray Analysis in Pediatric Disease Diagnostics and Clinical Research. Yiping Shen, Boston, MA
9:30 am    [6] Clinical Genomics in Pediatric Oncology. Katherine Janeway, Boston, MA
9:45 am    [7] Whole Exome Sequencing for Classical and Nonclassical Mendelian Contributions to Autism. Timothy Yu, Boston, MA
10:00 am    [8] Urine Proteomics for Discovery of Diagnostic Markers of Human Disease. Alex Kentsis, Boston, MA
10:15 am    Refreshments

Session B
Advances in Pediatric Pathology Diagnostics
Chairs: Robert E. Brown & Nina Tatevian

10:30 am    [9] New Entities in Vascular Anomalies . Harry Kozakewich, Boston, MA
10:45 am    [10] Paucicellular Specimens - Cytopathology and Electron Microscopy Can Save the Day in Diagnosis of CNS Pathology. Meenakshi B. Bhattacharjee, Houston, TX
11:00 am    [11] Eosinophilic Esophagitis in Pediatric Population: an Update. Nina Tatevian, Houston, TX
11:15 am    [12] Pediatric Tumors with EWS Gene Rearrangements - A Pathologic and Molecular Review. Sanda Alexandrescu, Boston, MA
11:30 am    [13] Neonatal Intrahepatic Cholestasis Associated with Citrin Deficiency (NICCD). John Hicks, Houston, TX
11:45 am    [14] Cystic Fibrosis or CFTR-Related Metabolic Disease (CRMS) a Diagnosis Obtained from Newborn Screening? Sidney M Hopfer, Farmington, CT
12:00 pm    [15] Newborn Screening for Severe Combined Immunodeficiency (SCID): A Pilot Study. Patricia Slev, Salt Lake City, UT
12:15 pm    [16] Pediatric Medical Renal Disease: 25 Year Retrospective Review at Texas Children’s Hospital. Karen Eldin, Houston, TX
12:30 pm    [17] Villin Immunohistochemistry is an Optimal Method for Diagnosing Microvillous Inclusion Disease. Nick Schillingford, Boston, MA

Luncheon sponsored by the Sections on Clinical Science in Practice and Clinical Molecular Biology & Genetics Brandeis/Holmes Room
Chair: Roland Valdes, Jr.

Session C
Research Frontiers: Bench to Bedside
Kennedy Room
Chairs: Robert L. Hunter & Roger L. Bertholf

2:00 pm    [19] SIDS and Serotonin. Hannah Kinney, Boston, MA
2:30 pm    [20] The Tumor Suppressor WTX in Cancer and Development.
  Miguel Rivera, Charlestown, MA
2:45 pm    [21] NUT Midline Carcinoma. Christopher French, Boston, MA
3:00 pm    [22] The Future of Cancer Therapy – Targeting the Antecedents of Cancer Cells. Thomas J. Lewis, Boston, MA
3:30 pm    Refreshments

3:45 pm    [23] The Clinical and Population Genetics of TMPRSS6-Dependent Regulation of Systemic Iron Homeostasis. Mark Fleming, Boston, MA
4:00 pm    [24] Pediatric MDS and Bone Marrow Failure. Inga Hofmann-Zhang, Boston, MA
4:15 pm    [25] Stem Cell MicroRNA Regulation of Neuroblastoma. John Powers, Boston, MA
4:30 pm    [26] Anaplastic Lymphoma Kinase (ALK) Tumor Vaccine in ALK+ Non Small Cell Lung Carcinoma (NSCLC). Roberto Chiarle, Boston, MA
4:45 pm    [27] Mutations in Lrp5 Improve Bone Density and Strength In A Mouse Model of Osteogenesis Imperfecta. Christina M. Jacobsen, Boston, MA
5:00 pm    [28] DNA Aneuploidy by Image Cytometry is a Better Marker for Esophageal Adenocarcinoma. Qin Huang, Boston, MA

5:30 pm    Adjournment

6:00 pm    Young Fellows Section  (see full announcement elsewhere) Beantown Pub, 100 Tremont Street
7:30 pm    Musicale rehearsal (organized by Myra L. Wilkerson) - Kennedy Room
7:30 pm    Awards Committee meeting (Sidney M. Hopfer, Chair), Gardner Room
8:30 pm    Nominating Committee meeting (Magali J. Fontaine, Chair), Gardner Room

Friday, 24 May

(The Brigham & Women's Hospital)
(Bus leaves Hotel at 7:15 am)

Session D
Clinical Science in Practice
Department of Pathology, Cotran Conference Room
Chairs: Kilmer McCully & Kyle Kurek

8:00 am    [29] Back to the Future: Pathology as the Foundation of Care. Jeffrey Alan Golden, Boston, MA
8:15 am    [30] Utility of Lean in Clinical Laboratories. Stacy E.F. Melanson, Boston, MA
8:30 am    [31] Mutational Profiling of Every Cancer Patient in an Institution. Laura MacConaill, Boston, MA
8:45 am    [32] Molecular Diagnostics in Clinical Microbiology. Lynn Bry, Boston, MA
9:00 am    [33] Laboratory Automation for High-Throughput Chemistry and Clinical Trials. Petr Jarolim, Boston, MA
9:15 am    [34] Using Clinical Laboratory Informatics to Improve the Diagnostic Process. Anand S. Dighe, Boston, MA

9:45 am    Refreshments

Session E
Tour of the Research Labs of The Brigham & Women’s Hospital
Chairs:  Juliana Szakacs & Kyle Kurek

10:00 am    New Cardiac Biomarker panels in the Clinical Reference Lab for Research. Petr Jarolim, Boston, MA
10:22 am    Next Generation Sequencing – Molecular Lab. Neal I. Lindeman, Boston, MA
10:45 am    Molecular Microbiology Lab. Lynn Bry, Boston, MA
11:07 am    Lean Workflow in the Lab. Stacey Melanson, Boston, MA
11:30 am    Bus leaves to return to the Omni Parker House Hotel
12:45 pm    Bus leaves the Omni Parker House Hotel for the optional tour of Boston waterfront and Museum of Fine Arts (open to participants and accompanying persons)
5:30 pm    Bus leaves to return to the Omni Parker House Hotel

Annual Reception and Banquet
Alcott Room
(7:00 pm, the Omni Parker House Hotel)

Toastmaster: Roland Valdes, Jr., Louisville, KY
Young Clinical Scientist Award presented by Sidney M. Hopfer to Joshua A. Bornhorst, Little Rock, AR
Young Clinical Scientist Award presented by Sidney M. Hopfer to Kristine E.  Konopka, Houston, TX
Young Clinical Scientist Award presented by Sidney M. Hopfer to Lori M.  Millner, Louisville, KY
Young Clinical Scientist Award presented by Sidney M. Hopfer to Frederick G. Strathmann IV, Salt Lake City, UT
Diploma of Honor presented by Charles D. Hawker to Vincent A. DeBari, South Orange, NJ
Clinical Scientist of the Year Award presented by Myra Wilkerson to Clive R Hamlin, Cleveland, OH
Gold Headed Cane Award presented by Roland Valdes, Jr. to John Savory, Charlottesville, VA
Banquet address: H. Eugene Lindsey, President and CEO, Atrius Health “Changes in Healthcare under the ACA and the Pioneer ACO”

Saturday, 25 May

(Omni Parker House Hotel)

6:15 am    Run-for-the-Lilies: 2.5- and 5-mile running/walking event organized by Robert Hunter & Consolato Sergi for the Committee on Athletics
7:00 am    Breakfast meeting of the Membership Committee,
Kilmer McCully, Chair

Session F
Poster Presentations
Kennedy Room
Chairs: Charles D. Hawker and Joshua Bornhorst

8:00 am    [35] Mobile Computing Platform with Decision-support Modules for Hemotherapy. RichardHuang, Houston, TX
8:06 am    [36] Pigmented Hepatocellular Adenoma: Microscopic and Morphoproteomic Correlates of Testosterone-Associated Oxidative Stress. Jennifer E. Dierksen, Houston, TX
8:12 am    [37] Acute Megakaryoblastic Leukemia and Primary Mediastinal Germ Cell Tumor in a Patient with Benzene Exposure. Shakuntala Mauzo, Houston, TX
8:18 am    [38] Morphoproteomics Identifies Etoposide Resistance Signature in Neuroendocrine Carcinoma with Therapeutic Alternatives. Kristine Konopka, Houston, TX
8:24 am    [39] Congenital Nephrotic Syndrome of Finnish Type with Nephrin Mutation in Fraternal Twins. John Hicks, Houston, TX
8:30 am    [40] Pigmented Microphages in Pediatric Colonic Biopsies: Clinical Pathological Correlation. Alyaa Al-Ibraheemi et al, Houston, TX
8:36 am    [41] Ehlers-Danlos Variant of Periventricular Nodular Heterotopia, and Severe Lung Disease: Report of a Case with Discussion of the Potential Molecular Mechanism. P. M. Rodriguez-Waitkus, Houston, TX
8:42 am    [42] Lipomatous Hemangiopericytoma of the Sellar Region: Case report and Review of the Literature. Yoshua Esquenazi, Houston, TX
8:48 am    [43] Antitumoral Effects of Metformin: Proteomics and Genomics of Neuroblastoma Cells. Priya Weerasinghe, Houston, TX
8:54 am    [44] First Report of Ehrlichia ewingii infection involving human bone marrow. M. Brandon Allen, Little Rock, AR

Session G
Clinical Science in Practice
Kennedy Room
Chairs: Vincent A. DeBari & Lori M. Millner

9:00 am    [45] Lipid Lowering and Anti-Atherosclerotic New Drug Based on Removal of Symbiotic Microbial Action. Maria Lourdes Higuchi, São Paulo, Brazil
9:15 am    [46] The Eye as a Window to the Pathology of Chronic Diseases. Clement L. Trempe, Boston, MA
9:45 am    [47] Services Provided by the National Prion Disease Surveillance Center. Clive R Hamlin, Cleveland, OH
10:00 am    [48] Validation of an Automated Camera System to Identify
Patient Name Mislabeled Specimens. Charles D. Hawker, Salt Lake City, UT
10:15 am    Refreshments

(Sessions H, I, & J are concurrent with Sessions K, L, & M)

Session H
Dermatopathology Slide Seminar
King Room
Chairs: Magali J. Fontaine & Egil Fosslien

10:30 am    [49] Update on Melanoma: Diagnosis and Management in the Molecular Era. Artur Zembowicz, Boston, MA
11:00 am    [50] Potential Role of Inflammation and Loss of Sebaceous Glands in Scarring Alopecia. Stephen Lyle, Boston, MA
11:30 am    [51] Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma. Christine Lian, Boston, MA
12:00 pm    Panel Discussion of member cases, Artur Zembowicz, Stephen Lyle, Christine Lian, Boston, MA

Luncheon sponsored by the Section on Clinical
Science in Practice, Brandeis/Holmes Room
Chair: Juliana Szakacs

12:15 pm    [52] Building the Lab in a Physician Group Practice ACO. Emily Brower, Joe Kimura, and Juliana Szakacs, Boston, MA

1:25 pm    Adjournment

Session I
Cell & Tissue Pathology
King Room
Chairs: Dani Zander & Myra Wilkerson

1:30 pm    [53] Molecular Characterization of Breast Cancer: Clinical Implication on Patients Management. Shahla Masood, Jacksonville, FL
2:00 pm    [54] Morphoproteomics in Personalized Cancer Therapy: Concept and Proofs of Concept with Response and Resistance Signatures. Robert E. Brown, Houston, TX
2:30 pm    [55] Sweet Dysgeusia: Is It Paraneoplastic? Bao T. Nguyen, Houston, TX
2:45 pm    [56] Malaria and the Mitochondrial Connection between Cancer Metabolism and Stemness. Eshel Ben-Jacob, Tel Aviv, Israel
3:00 pm    Refreshments

Session J
Cell & Tissue Pathology 2
King Room
Chairs: Kathleen A. Allen & Joseph C. Parker

3:15 pm    [57] Histologic Evidence of Change in Inflammation Due to Isoniazid Hepatotoxicity. Anand Gourishankar, Houston, TX
3:30 pm    [58] Pediatric Pulmonary Neoplasia: Current Perspectives. John Hicks, Houston, TX
4:00 pm    [59] Morphoproteomics Characterizes Aberrant Crypt Foci and Adenomatous Polyp Formation in Familial Adenomatous Polyposis: A Case Report with Therapeutic Implications. Alyaa Al-Ibraheemi et al, Houston, TX
4:15 pm    [60] Clonally Distinct Plasma Cell Neoplasms and Low Grade B-Cell Lymphomas in the Bone Marrow. Daniela Hoehn, New York, NY
4:30 pm    [61] Cryopreserved Human Amniotic Membrane Scaffold (CAS) to Promote Healing of Iatrogenic Fetal Membrane Defect in A Swine Model. Ramesha  Papanna, Houston, TX

Session K
Clinical Pathology / Microbiology
Kennedy Room
Chairs: John Savory & Joseph A. Knight

10:30 am    [62] From Tragedy to Triumph to Trepidation Antibiotics at Age 70. Stephen Brecher, Boston, MA
11:00 am    [63] Archaea, Metalloprotease, Mycoplasma Pneumoniae and Plaque Vulnerability. Maria Lourdes Higuchi, São Paulo, Brazil
11:30 am    [64] Alzheimer’s disease a Spirochetosis. Past and Recent  Evidences in Favor of Causality. Judith Miklossy, Martigny-Combe, Switzerland
12:00 pm    [65] Evaluation of Two Respiratory Virus Panel Assays. Frederick L. Kiechle, Hollywood, FL

12:15 pm    Luncheon recess listed following Session H

Session L
Clinical Science in Practice/ Toxicology
Kennedy Room
Chairs: Frederick L. Kiechle & Philip R. Foulis

1:30 pm    [66] Case report: Zinc-induced Urinary Retention in a Patient with a Urethral Stricture. John Savory, Charlottesville, VA
1:45 pm    [67] Potential Utilization of Serum Concentration to Screen for Alpha 1-Antitrypsin Deficiency. Joshua Bornhorst, Little Rock, AR
2:00 pm    [68]Advancements in Analytical Methods for Immunosuppressive Drug Testing. Kamisha L. Johnson-Davis. Salt Lake City, UT
2:15 pm    [69] High Prevalence of Multiple Autoimmune Antibodies in Type 1 Diabetes Mellitus Patients. Pai C Kao, Rochester, MN
2:30 pm    [70] Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics. Lori M. Millner, Louisville, KY
2:45 pm    [71] Diagnosing POEMS Syndrome: the Important Role of the Laboratory Practitioner. Stanley S. Levinson, Louisville, KY
3:00 pm    Refreshments

Session M
Blood Banking and Transfusion Medicine
Kennedy Room
Chairs: Pai C. Kao & Gifford Lum

3:15 pm    [72] Successful Clinical Management of Platelet Utilization in a Tertiary Teaching Hospital. Fouad Boctor, Manhasset, NY
3:30 pm    [73] Comprehensive Coagulation Testing and Transfusion Algorithms for Management of Cardiopulmonary Bypass Coagulopathy. Andy Nguyen, Houston, TX
3:45 pm    [74] Causes of Any-Cause Readmissions within 30-days of a
Prior Heart Failure Hospitalization. Philip R. Foulis, Tampa, FL
4:00 pm    [75] Fever, Hemolytic Anemia and Thrombocytopenia in a
Patient with Transfusion Transmitted Babesiosis. Gifford Lum, Boston, MA
4:15 pm    [76] A Novel Method for the Assessment of Lead Exposure in
Pediatric Transfusions. Frederick G. Strathmann, Salt Lake City, UT
4:30 pm    [77] Comparison of Vit D Measurement by the Siemens Immunoassay and 2 Separate LC/MS/MS Methods. Zakaria Ahmed, Boston, MA

4:45 pm    Business Meeting of the Association, Kennedy Room
Roland Valdes, Jr., President

Musicale and Art Show
Kennedy Room
7:30 pm
with wine and cheese reception during intermission.
Organized by Myra L. Wilkerson, Chair of the Committee on Music and Fine Arts

Activities of the Auxiliary
Under the leadership of Gerry Savory, an excellent program for the Auxiliary has been planned for the Boston annual meeting. The activities include refreshments in Kathie Valdes’ room Wednesday evening, a meeting and luncheon at the home of Nina McCully in Winchester on Thursday, a guided tour of the Massachusetts State House on Friday morning, and a Freedom Trail tour on Saturday morning including a luncheon at the 21st Amendment Restaurant. Check at the registration desk or with members of the Auxiliary for specific details on these planned events.

Inaugural Meeting and Dinner
Young Fellows Section

by Joshua Bornhorst

The inaugural meeting of the Young Fellows Section of the Association of Clinical Scientists will be held Thursday night during the annual meeting of the Association.  At this informal gathering new and young members of this society will discuss the formation of a formal group within the Association and potential related leadership, mentoring, and publication opportunities. In addition, this is a great chance to get to know your peers as well as those on the Executive Committee. Although subject to revision, the tentative guideline for joining this group are all clinical scientists under the age of 40, in training, or within five years of completion of training.

The meeting will be held at 6 PM on Thursday May 23rd, at the Beantown Pub, 100 Tremont Street, Boston.  This classic pub is on the Freedom Trail in downtown, about two blocks from our hotel.   Sign up at the meeting for a mere $10, which will cover food and appetizers.  The organizational portion of the meeting will likely be finished by 8 or so, but there will likely be further “networking” after that.  Hope to see you there.

Run-for-the-Lilies
The Run-for-the-Lilies, an annual 2.5 or 5.0 running and/or walking event, will be held at 6:15 am on Saturday morning. It is being organized by the Athletics Committee (Consolato Sergi, Chair and Robert Hunter) and will likely be along a portion of Boston’s famous Freedom Trail.

Abstract Instructions

The deadline for abstract submission has passed and abstracts can no longer be accepted.

CME Accreditation Statements

Accreditation. This activity has been planned and imple­mented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the College of American Pathologists (CAP) and the Association of Clinical Scientists. The College of American Pathologists is accredited by the ACCME to provide continuing medical education for physicians.
 
Continuing Medical Education Designation (CME). The College of American Pathologists  designates this live educa­tional activity for a maximum of  20.00 AMA PRA Category 1 Credits TM. Physicians should claim only credit commensurate with the extent of their participation in the activity.
 
Continuing Education (CE) for Non-physicians Designa­tion. The College of American Pathologists  designates this live educational activity for a maximum of  20.00 credit hours of continuing education. Participants should  claim only credit hours commensurate with the extent of their participation in the activity.
 
ASCP Statement. This activity is acceptable to meet the continuing education requirements for the ASCP Board of Registry Certification Maintenance Program.
 
California and Florida Statement. This activity is approved for continuing education credit in California and Florida. Florida non-physicians must provide their license numbers.
 
Disclaimer. The content of this CME activity does not necessarily reflect the view or policies of the College of American Pathologists.
 
Educational Goals. At the end of this educational session the participant should be able to
                (a) Interpret, discuss, appraise, and apply in the clinical arena various recent advances in genetic testing and the diagnosis of pediatric disorders.
                (b) Interpret and apply laboratory techniques for cancer morphoproteomics and immunohistochemical profiling of morphoproteomic patterns.
                (c) Interpret, discuss and apply new clinical approaches to individualize or personalize diagnostic testing and pharmacogenomics.
                (d)  Interpret and apply laboratory techniques for metabolic profiling in the clinical toxicology setting.
                (e) Interpret, discuss, and apply in the clinical setting various recent advances in the diagnosis of dermatological disorders including the evaluation of malignant melanoma.
 
Educational Needs. Specific educational needs of the target audience include: (a) technical and diagnostic integration of morphoproteomics for surgical pathology and appropriate selection of clinical therapeutic models; (b) methods for consultative integration of pharmacogenomic data for personalized medical care; (c) alternative models and methods for metabolic profiling in toxicology; (d) methods for improving safety and specimen integrity using automation in the clinical laboratory.
Professonal Practice Gaps. The professional practice gaps that are the primary target of this program are: (a)disparity between the state-of-the-art in genetic sequencing and molecular testing for genetic disorders and pediatric pathology and current practices; (b) disparity between the state-of-the-art in cancer morphoproteomics and the availability of immunohistochemical profiling in the current clinical laboratory; (c) disparity between current practices in laboratory medicine and new clinical approaches to individualization or personalization of laboratory tests, especially in respect to pharmacogenomics; (d) disparity in current laboratory practices in toxicology and state of the art metabolic profiling; (e) disparity in state of the art diagnosis of malignant melanoma and other dermatologic disorders and current practice.
 
Evidence-based Recommendations. The College of American Pathologists and the Association of Clinical Sci­entists are dedicated to promoting improvements of quality in healthcare and not a specific proprietary business interest or a commercial interest. Therefore the College of American Pathologists and the Association of Clinical Scientists expect all planners/faculty/authors of these educational activities to make all recommendations and/or planning criteria involv­ing clinical medicine to be based on evidence that is accepted within the profession of medicine as adequate justification for these indications and contraindications in the care of patients.
 
Methods and Evaluation. This program will use lectures, case discussions, a technical workshop, a tutorial session, and question-and-answer opportunities as primary educational methods. A course evaluation form will provide participants with the opportunity to assess each session and speaker, to identify future educational needs, and to comment on any perceived commercial bias in the presentations.
 
Disclosure Statements. All faculty, planners, and authors of a CAP educational activity must disclose to the program audience any financial interest or relationship with the manufacturer(s) of any commercial product(s) that may be discussed in the educational activity or with the manufacturer of a product that is directly competitive with a product dis­cussed in the presentation.  Relevant financial relationships are considered to be any financial relationships in any amount occurring within the past 12 months that create a conflict of interest.
 
The College of American Pathologists does not view the exis­tence of these interests or uses as implying bias or decreasing the value to participants. The CAP, along with the Accredita­tion Council for Continuing Medical Education (ACCME), feels that this disclosure is important for the participants to form their own judgments about each presentation.  The pro­gram contains a list of the financial disclosure relationships for anyone who was able to affect content of this educational activity.
 
The CAP does identify and manage all potential conflicts of interest to ensure that all educational activities promote im­provements or quality in healthcare and are free of commer­cial bias for or against a product/service. 

Registration

The regular full registration fee is $535. Emeritus Members, Junior Members, and residents or post-doctoral fellows may pay a reduced fee ($275). The registration includes a ticket to the reception and banquet on Friday evening. Extra banquet tickets are $95. The two luncheon seminars are $40 each. Tickets to the Friday afternoon tour of the Boston waterfront and the Museum of Fine Arts are $50. Residents and fellows presenting papers will receive a complimentary registration for that day, but this excludes tickets to the luncheons, banquet, or tour.

In order to obtain Continuing Medical Education (CME) credits, one must register for the full meeting (the two options above). One day complimentary registrations without any CME are permitted for speakers attending just the day of their lecture. To obtain this registration send an email to the Association’s email address clinsci@sover.net. Please provide your full contact information. This complimentary registration is not available through the Online registration system noted below.

On-line registration through a secure website is available by clicking the button below. Alternately, you can print a registration form from this PDF and fax or mail your registration form to the fax number or Association address shown on the form.

Register Online for Annual Meeting

Accommodations & Transportation

Hotel Accommodations

The Omni Parker House Hotel, 60 School Street, Boston, MA 02108, phone (617) 227-8600, fax (617) 742-5729 is the headquarters hotel for the meeting and most activities. This grand luxury hotel has been symbolic to Boston’s rich history and culture since 1855. Old world charm and elegance are accompanied by all of the modern conveniences of a world-class establishment. Nestled in the heart of downtown Boston, the Omni Parker House is located along the Freedom Trail and at the foot of Beacon Hill, Boston Common, Quincy Market and Faneuil Hall marketplace. It is only a short walk to Boston Harbor. Parker’s Restaurant is the home of the Parker House Roll and the Boston Cream Pie.

The Parker House Hotel is a 100% non-smoking luxury hotel. In 2012 it was rated “Highest in hotel guest satisfaction among upper-upscale hotel chains” by JD Power and Associates and lists numerous other awards and accolades on its website, such as being voted “Best place for rekindling romance” by CBS Boston. The special convention rate will be $245/room (single or double) plus taxes and fees (currently, 14.45%). The cut-off date for room reservations at the guaranteed conference rate is Wednesday, May 1, 2013. The Omni Parker House hotel has established a link on their web site through which you can obtain your hotel reservations for our meeting. That link is: http://www.omnihotels.com/FindAHotel/BostonParkerHouse/ MeetingFacilities/AssociationofClinicalScientistsConference5.aspx

Please do not wait until the last minute to obtain your room. Boston is a destination of great attraction. In contrast to our meetings in Louisville and Mobile when our hotels graciously extended our reservation period, one should not assume the Parker House will be so inclined. The rack rate if you miss the cut-off date is currently $279 plus taxes and fees.

Transportation

The hotel does not provide shuttle service from Boston Logan International Airport. However, the airport is only 2.3 miles (10 minutes, depending on traffic) from the hotel. Local taxi cabs are recommended and the fares will range from $20-28 depending on traffic.

Future Meetings

2014

Amelia Island, Florida, hosted by University of Florida, Jacksonville. Dr. Roger Bertholf, Meeting Chairperson.

2015

Park City, Utah, hosted by University of Utah School of Medicine and ARUP Laboratories. Dr. Charles D. Hawker, Meeting Chairperson.

Archive of Past Meetings

Highlights of 131st Meeting, Louisville, Kentucky May 18-22, 2011



In Memory of F. William Sunderman, Jr., MD, (June 23, 1931 – April 1, 2011)

The 131st meeting of the Association of Clinical Scientists was held in memory of Bill Sunderman, Jr., who served the Association for 42 years as Secretary-Treasurer, as Editor-in-Chief of the Annals of Clinical and Laboratory Science, and in numerous other capacities.

F. William Sunderman Jr. (Bill), who died on April 1, 2011 at the age of seventy-nine was, like his illustrious father of the same name, a physician and scientist, both of whom made many significant contributions to the field of laboratory medicine and especially the sub-specialty of nickel toxicology. Both father and son were devoted servants of the Association of Clinical Scientists as founders, scientific meeting organizers and editors of the Annals of Clinical and Laboratory Science. Bill was born in Philadelphia, Pennsylvania on June 23, 1931. He graduated as valedictorian from Central High School in Philadelphia in 1948 and with a BS degree from Emory University in Atlanta in 1952. He underwent his medical training at Thomas Jefferson University in Philadelphia where he obtained the M.D degree in 1955. From 1955 to 1956 he was an intern at Thomas Jefferson University and from 1956-58 a fellow in metabolic research at the same location. It was at this time that Bill considered specializing in nephrology but the depressing nature of this field before hemodialysis treatment was developed discouraged him and he entered the same field as his father namely clinical pathology. His first foray was as the Chief of the Clinical Chemistry Service at the US Naval Medical School in Bethesda Maryland from 1958-60. At this time He was a lieutenant in the US Navy. It is evident that Bill’s primary interest was in clinical chemistry since his first publications beginning with “The clinical significance of measurements of protein-bound iodine (1954)” could all be classified as belonging to this discipline. Following a spell (1961-64) as Instuctor in Medicine, Thomas Jefferson University, Philadelphia, Bill took on even more onerous service and academic responsibility by moving to the Department of Pathology at the University of Florida in Gainesville, Florida where he was Director of Clinical Laboratories and Associate Professor of Pathology. The Shands Teaching Hospital at the University of Florida opened just six years before Bill’s arrival but already had an excellent tradition in clinical pathology since the first director of laboratories was Dr. John Bernard Henry, a distinguished pathologist who went on to make many significant contributions. Bill fitted well into the clinical laboratory and put together an excellent staff of faculty and technical experts. One change that he did make, however, was brought about when the processing of a seventy-two hour fecal fat specimen which required homogenization on a paint can shaker. The container’s lid came loose during the shaking process resulting in an environmental disaster throughout the clinical laboratory. Thereafter, Bill decreed that the processing should take place in a more remote and contained place. Bill exhibited considerable administrative skills in directing and developing the clinical laboratory services. He initiated the development of one of the first clinical laboratory computer systems complete with cumulative reporting and, for the first time, the application of delta checking of results. He also was interested in developing more sophisticated analytical techniques, something that was part of his legacy for the next four decades. However, it was the creation of a research program in concert with his service and teaching skills that shaped the start of his academic career in a leadership position. Bill was well funded by the American Cancer Society and his laboratory focused on nickel carcinogenesis. He was remarkably creative: he had, as aptly stated by his department chairman Dr. Joshua Edwards, “the ability to shed ideas like water off a duck’s back”. A steady stream of papers came out of his laboratory creating new avenues of research. Bill was also a gifted teacher and his lectures, especially those presented to the medical students were well-organized, well-prepared and well-received by his audience. Throughout his life Bill had little interest in sports but he did attend the University of Florida football games, probably because he lived just across the street from Florida Field, the home of the Fighting Gators. Bill’s wife, Carolyn, came to the University of Florida as a resident in pediatrics and they resided in a lovely comfortable home near the university and it was here that their first child was born. It was also at the University of Florida that Bill was starting to attract students to his laboratory, many from outside the United States. This continued in his later career and many distinguished medical scientists from countries around the world, including Poland, Yugoslavia, Japan and many others spent time in Bill’s laboratory and took their knowledge acquired there to establish their own research programs.

In 1968, after achieving the academic rank of full professor and having established himself as an internationally recognized leader in laboratory medicine, Bill decided to move on to the next step: that of department Chair. He received several offers, some from well-established programs, but eventually decided on a newly established medical school in Farmington, Connecticut as part of the University of Connecticut. His position would be as chairman of the department of laboratory medicine, one of the few departments at that time to be separate from the department of pathology. He also was given a joint appointment as professor of pharmacology. Bill’s rationale reasoned that in becoming head of a new department in a new medical school he could form and shape it according to his own vision; what developed would depend largely on his leadership. He went to Farmington inheriting no “baggage”. He also felt that a smaller hospital, as the Shands Teaching Hospital in Florida was during his tenure there, minimized his time spent on administrative duties providing more time for research and other academic activities. At the time of his arrival exchanging the colder climes of New England from the warmth of Florida, the new hospital and medical school in Farmington was just a large hole in the ground. His clinical and research laboratories were situated at the McCook Hospital in Hartford. Eventually the new facility was complete and Bill spent the next twenty-nine years directing a vibrant and productive program. He was now in his prime. His research developed along new lines of investigation, as is the case with all research programs, but the main focus was on the chemical toxicology and clinical chemistry of metals with nickel, of course, being the primary metal of interest. Bill maintained a high and consistent level of funding from The National Institutes of Health, The American Cancer Society, The United States Department of Energy, The Environmental Protection Agency and others throughout his career during which he published two hundred and fifty-eight articles in refereed journals, eighty-seven articles in monographs, manuals and texts, and eighteen books. As he told his junior faculty and students, “Publications are the best form of insurance for the academician”.

Almost all energetic, ambitious and successful scientists eventually become involved in national and international scientific organizations. For many years (1972-1988), Bill focused his considerable degree of energy on the International Union of Pure and Applied Chemistry (IUPAC), Clinical Chemistry Division. His efforts were mainly directed towards the Commission on Toxicology and its various subcommittees particularly the Nickel Subcommittee. The international nature of IUPAC provided Bill with the opportunity to travel and to apply his scientific and organizational skills worldwide. The Commission on Toxicology held their first international meeting in Monte Carlo in 1977 with, and under Bill’s leadership, it enjoyed considerable success. Many other meetings followed including several of the Nickel Subcommittee which was well supported by the nickel-producing industry. The well-known problem of nickel carcinogenesis in nickel-producing workers was of concern to the industry and Bill’s efforts added greatly to the understanding and prevention of this devastating problem in these workers. It was at the last IUPAC meeting that Bill helped to organize that his skills and knowledge were so evident. With his usual talent he planned the scientific program putting together a cohesive schedule that would not be instinctive to most people but which was second nature to Bill. The conference was in Vancouver, Canada and when the time came for him to present his own paper he was asked a question during the discussion period as to the pH of some reagent. He immediately gave the correct answer to two decimal places demonstrating his comprehensive knowledge of the experiments that had been carried out in his laboratory. Bill’s involvement in IUPAC inspired many young scientists and allowed him to interact with people who were working in fields different from his own. He was also involved in other international organizations including the International Federation of Clinical Chemistry, International Commission on Occupational Health and others, but none occupied his energies as much as IUPAC. This International involvement allowed Bill to interact with scientists around the world, creating an aura of good fellowship that he cherished.

Bill gave a lifetime of service to the Association of Clinical Scientists which had been founded by his father. He served as president 1964-65 and in 1969 upon the death of Dr. Bob McFate, he took over as secretary-treasurer; Bill held this position until his own death. On top of these burdensome duties, in 1999 he added those of editor-in-chief of the Annals of Clinical and Laboratory Science again holding this position until his death. He took over from his father, the first editor who decided to “take a breather” at the age of 101. Bill played a major role in the planning and organization of the Association meetings and always did an on-site visit in order to work with the local committee. He always put together the finishing touches making sure that the meeting rooms were wide and spacious rather than long and narrow, and that the meals and refreshments were appealing but not extravagant. The scientific program was his specialty and, as stated earlier, he had a knack of putting together cohesive sessions and would bracket a speaker “of limited ability” with a couple of excellent presentations. (He learned this trick from his Father of course.) Bill was always kind to speakers especially to young clinical scientists embarking on their careers. He would remark “Wonderful paper and great presentation – your best ever” to inspire confidence in those unsure of their abilities.

Bill always was a key performer in the Musicale, since the early 1970s a feature of the Association meetings. Many of us have fond memories of Bill, his father and a few other highly talented musicians who were Association Members, entertaining us with accomplished performances of chamber music. Bill was a gifted violist having decided early in life not to follow his Father in everything. Bill Senior was a violinist who had the distinction of owning several wonderful instruments including a Stradivarius known as the Irish Strad. Bill Junior eventually inherited this violin, which he sold and used the proceeds to buy a really excellent viola, something he enjoyed immensely. The Arts, especially chamber music, were most important to Bill, and provided a means of bonding with his professional and social friends and family. He will be intensely missed by a remarkable diversity of friends. Many of these friends bonded with Bill and his family through weekly evenings of chamber music. These sessions were typically followed by convivial and uplifting conversation.

Bill achieved many awards throughout his career, the major ones being as follows: The Ames Award for Outstanding Contributions to Clinical Chemistry from the American Association for Clinical Chemistry (1978); Clinical Scientist of the Year (1976), Recipient of Gold Headed Cane (1998) and Diploma of Honor for Outstanding Contributions to Clinical Science (2007) from the Association of Clinical Scientists; Achievement Award for Research on Nickel Toxicology (1992) and Chemistry and Human Health Division Award for Leadership Clinical Chemistry and Toxicology (2010) from IUPAC.

Bill retired from the Chair of Laboratory Medicine at the University of Connecticut in 1997 and he and his wife Carolyn moved to Whiting, Vermont. In his retirement he was a research professor of pathology at the University of Vermont, and a visiting scholar in chemistry and biochemistry at Middlebury College while continuing his extensive duties for the Association of Clinical Scientists.

From the 1970s onwards, Bill and Carolyn always had owned a series of Labrador Retrievers each of which he adored. The first one was acquired at an Association meeting in Washington and came from a noted breeder in Middleburg, Virginia; the contact being made by this writer.

Bill's beloved wife, Carolyn predeceased him in 2002. His brother, Joel Baily Sunderman, and sister, Louise Lehr Sunderman also predeceased him. He is survived by his daughter and son-in-law, Emily L. Sunderman and Michael J. Lee, of Cornwall; daughter and son-in-law, Elizabeth R. Sunderman and Robert C. Hauck of Salt Lake City, Utah; son and daughter-in-law, Frederick W. Sunderman III and Kathleen L. Sunderman of Freeland, Michigan; mother-inlaw, Frances L. Reynolds of Chestertown, Maryland; grandson, Carter S. Lee of Cornwall; granddaughters, Hailey L. and Caitlin E. Hauck of Salt Lake City; grandson, F. William Sunderman IV, and granddaughter, Chloe E. Sunderman of Freeland, Michigan.

Dr. F. William Sunderman Jr. was much loved by his family, friends, colleagues and many in the scientific community. He was kind, helpful and full of encouragement and had a broad range of interests and talents. We can hope but not expect to see his like again.

John Savory,
Charlottesville, Virginia


Claude P. Brown Memorial Lecture

James L. Wittliff, Ph. D., M.D. hc, FACB: Deciphering the genomics and proteomics of human cancer to predict clinical behavior.

Professor Wittliff’s team is internationally regarded for studies of estrogens and their mimics with receptor proteins in human cancer, exploiting proteomics and genomics. His laboratory was among the first to report estrogen receptors in a breast cancer biopsy predicted a patient’s response to hormone therapy. This finding led to collaborations with the NSABP, establishing Tamoxifen as adjuvant therapy for breast cancer and use of receptors as biomarkers of patient prognosis and response. With NEN/DuPont, Dr. Wittliff developed the original FDA-approved kits for assessing estrogen and progestin receptors in biopsies, celebrated as a major contribution to laboratory medicine. His laboratory, designated the National Reference Facility for historical clinical trials in North America, served more than 400 laboratories worldwide. Focusing expertise on molecules exhibiting estrogen mimicry, Dr. Wittliff and IA, Inc. patented receptor-based biosensors detecting endocrine-disrupting compounds in the environment. Awards include Outstanding Contributions to Clinical Chemistry from the AACC, Goldsmith Research Excellence Award from the American Cancer Society and the University of Louisville President's Award for Career Achievements. More than 200 students and research fellows from 45 countries have trained in his laboratory. Currently Dr. Wittliff directs the Institute for Molecular Diversity & Drug Design, which he co-founded.


Clinical Scientist of the Year Award

Presented to Roland Valdes, Jr., PhD by Magali Fontaine, MD, PhD

Dr. Valdes is Professor and Senior Vice-Chairman in the Department of Pathology and Laboratory Medicine, University of Louisville School of Medicine. He is also Professor of Biochemistry and Molecular Biology, serves as Chief of Clinical Chemistry and Toxicology and is the founder and director of a Postdoctoral Fellowship Program in Clinical Chemistry in the Department of Pathology and Laboratory Medicine. Dr. Valdes is nationally and internationally recognized as a leader in advancing the profession of clinical chemistry through his major contributions in promoting clinical chemistry as a discipline via the scholarships of clinical service, research, and teaching. As a result of these activities, Dr. Valdes has played a major role in heading and participating in numerous national committees and in leading several of our key professional organizations. He has served as president of the Clinical Ligand Assay Society (CLAS), president of the National Academy of Clinical Biochemistry (NACB), and is a past-president of the Commission for Accreditation in Clinical Chemistry (ComACC). Dr. Valdes has also served on the Board of Directors of the American Association for Clinical Chemistry (AACC) and as a director on the American Board of Clinical Chemistry (ABCC). Additionally, Dr. Valdes has been engaged in many other national work groups including federal government advisory committees. His scientific interests involve discovery and characterization of the mammalian cardenolides and their pathophysiologic role in cardiovascular disease and, more recently, in cancer therapeutics. For this scientific work, he has been awarded numerous grants from the NIH and other public and private organizations as well as several distinguished scientist awards from professional organizations such as the NACB, the CLAS, and the ACS. Dr. Valdes has authored more than 250 publications. In addition to his other research laboratories, Dr. Valdes is the principle founder and President of the Pharmacogenetics Diagnostic Laboratory at the University of Louisville where he is currently working on transitioning the science of pharmacogenetics and proteomics into clinical laboratory practice.


Diploma of Honor

Presented to Charles D. Hawker, PhD, MBA by Robert L. Hunter, Jr., MD, PhD

Dr. Charles Hawker is Scientific Director for Automation and Special Projects at ARUP, where he has been for 19 years. Dr. Hawker is also Professor (Adjunct) of Pathology in the University of Utah, School of Medicine. Previously, over a twenty year period, he held various positions in research and development and management at Laboratory Procedures, Inc. (Upjohn) and SmithKline Beecham Clinical Labs. At ARUP he has installed several major automation and robotic systems that have made ARUP one of the country’s most automated laboratories. He is a past president of the Association of Clinical Scientists, the National Academy of Clinical Biochemistry (NACB), and the Clinical Ligand Assay Society (CLAS). He has received the John V. Bergen Award of the Clinical and Laboratory Standards Institute (CLSI), the Professor Alvin Dubin Award from the NACB, and the Becton Dickinson Award from the Association for Laboratory Automation.

He has chaired automation committees in both CLSI and Health Level 7 and recently chaired the CLSI Subcommittee on Specimen Labels: Content and Location, Fonts, and Label Orientation. He is a co-author or author of four book chapters on clinical laboratory automation and a frequent lecturer on laboratory automation to national and international audiences. He has three issued patents and has published 40 peer-reviewed papers, 13 book chapters or invited reviews, and 42 abstracts. His most recent research efforts have focused on the use of machine vision systems for automated quality inspection of clinical laboratory specimens, particularly the development of an automated camera system that uses optical character verification (OCV) to identify mislabeled specimens.


Young Clinical Scientist of the Year Award

Presented to Peter C. Hu, PhD by Armand B. Glassman, MD

Dr. Peter Hu is an Associate Professor in the School of Health Professions (SHP) and is Director for the Molecular Genetic Technology Program. He received his Bachelor’s degree from Purdue University in 1990 with a major in Psychology and a minor in Chemistry. He later received his Master’s degree from Lamar University majoring in Microbiology and subsequently a Doctor of Philosophy from Trident University International (TUI) Healthcare Administration and Molecular Genetics. Dr. Hu also holds 3 specialty clinical certifications in Molecular Biology, Cytogenetics, and Clinical Laboratory Science. He joined MD Anderson Cancer Center (MDACC) in1995 and has worked in both clinical and academic environments.

Dr. Hu was a founding faculty member in the SHP and played an important role in MDACC achieving degree granting status by the Texas Coordinating Board in 2002, the Southern Association for Colleges and Schools (SACS) accreditation in 2005, the addition of the junior year curriculum approval in 2008, and SACS reaffirmation in 2010. He was also instrumental in the approval of the Molecular Genetic Technology program by the Texas Coordinating Board in 2005 and the program’s professional accreditation by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) in 2005 and its reaffirmation in 2010.

Dr. Hu has taught over 28 courses within the SHP and has served or is currently serving as Chair or as member on 38 institutional committees. Dr. Hu has published over 100 abstracts, 17 papers, and 1 book chapter. He is on the editorial board for 3 journals and a column editor for another. He has received 41 recognitions and awards including the recent Young Clinical Scientist award from the Association of Clinical Scientists for his presentation on using saliva cells to detect microsatellite instability in hereditary non-polyposis colon cancer patients and their at-risk family members . Professionally, he has served as the President for Texas Association for Clinical Laboratory Science, Education Director and Chair of the Genetics Educators Committee for the Association for Genetic Technologist, Chair of the Molecular Scientific Assembly, Continuing Education Approval Committee, and Awards Subcommittee Chair for the American Society for Clinical Laboratory Science, a member of the Review Committee for Accredited Programs under NAACLS, and has served as a clinical laboratory science programs inspector for 10 year. Dr. Hu regularly presents at state, national, and international levels on topics dealing with genetics research, clinical laboratory sciences, and education.

Chronology of Previous Association Meetings

1. Sept 8, 1954; Shoreham Hotel, Washington, DC; US Naval Medical Center, Bethesda, MD (Workshop on Clinical Hemoglobinometry)

2. Nov 19-20, 1954; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

3. April 1-2, 1955; Kenmore Hotel; Harvard Medical School; New England Deaconess Hospital; Boston, MA

4. Oct 7-8, 1955; Shoreham Hotel, Washington, DC: US Naval Medical Center, Bethesda, MD (Workshop on Blood Glucose)

5. Dec 9-10, 1955; Drake Hotel; University of Chicago, Argonne Cancer Research Hospital; Chicago, IL

6. April 6-7, 1956; Raleigh Hotel; Arlington Hospital; Washington, DC (Adoption of Constitution)

7. Oct 5-6, 1956; Shoreham Hotel, Washington, DC; US Naval Medical Center, Bethesda, MD (Workshop on Serum Proteins)

8. Dec 7-8, 1956; Bellevue-Stratford Hotel; Thomas Jefferson Medical College; Philadelphia, PA

9. March 1-2, 1957; Sheraton Hotel; Northwestern University Medical School; Chicago, IL

10. July 15, 1957; Royal Army Medical College, London, UK (International Workshop on Hemoglobinometry)

11. Sept 27-28, 1957; Shoreham Hotel, Washington, DC; US Naval Medical Center, Bethesda, MD (Workshop on Serum Cations)

12. Dec 13-15, 1957; Bellevue-Stratford Hotel; Thomas Jefferson Medical College; Philadelphia, PA

13. May 9-11, 1958; Sheraton-Lincoln Hotel; Indianapolis General Hospital; Eli Lilly Co; Indianapolis, IN

14. Oct 10-12, 1958; Park-Sheraton Hotel; New York, NY

15. Feb 26-Mar 1, 1959; Holiday Inn; Mobile Infirmary; Mobile, AL

16. Oct 9-11, 1959; Sheraton-Park Hotel; Washington Hospital Center; Washington, DC

17. March 3-5, 1960; DeWitt Clinton Hotel; Wadsworth Laboratory of NY State Health Department; Albany, NY

18. Nov 4-6, 1960; Shoreham Hotel; Washington Hospital Center; Washington, DC (Exocrine and Endocrine Functions of the Pancreas)

19. April 14-16, 1961; Bellevue-Stratford Hotel; Thomas Jefferson Medical College; Philadelphia, PA

20. Oct 27-29, 1961; Shoreham Hotel; Washington Hospital Center; Washington, DC (Thyroid and Parathyroid Functions)

21. April 6-8, 1962; Sheraton Hotel; Northwestern University Medical School; Chicago, IL

22. Oct 25-28, 1962; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Hemoglobin, its Precursors and Metabolites)

23. April 25-28, 1963; Sheraton Hotel; Louisville Medico-Chirugical Society; Louisville, KY

24. Oct 24-27, 1963; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Serum Proteins and the Dysproteinemias)

25. May 1-3, 1964; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

26. Nov 13-15, 1964; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Serum Electrolytes)

27. April 29-May 2, 1965; Statler-Hilton Hotel; St. Albans Naval Hospital; New York, NY

28. Nov 11-14, 1965; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of Infancy)

29. April 29-May 1, 1966; Palmer House; Chicago Board of Health Laboratories; Chicago, IL

30. Oct 20-23, 1966; International Inn; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Liver Diseases)

31. May 4-7, 1967; Robert Meyer Hotel, Orlando, FL; Kennedy Space Center, Cape Canaveral, FL; University of Florida College of Medicine, Gainesville, FL

32. Nov 2-5, 1967; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Kidney Diseases)

33. May 16-19, 1968; Peck Inn; University of Arkansas Medical School; Little Rock, AR

34. Nov 7-10, 1968; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Diseases Caused by Toxic Agents)

35. April 24-27, 1969; Malaga Inn; Mobile Infirmary; Mobile, AL

36. Nov 6-9, 1969; Mayflower Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Endocrine Disorders)

37. April 23-26, 1970; Ponchartrain Hotel; Wayne State University Medical School; Detroit, MI

38. Nov 6-8, 1970; Shoreham Hotel; Washington Hospital Center; Washington, DC (Chemical Hematology)

39. April 22-25, 1971; Hotel Sonesta; University of Connecticut Medical School; Hartford, CT

40. Nov 11-14, 1971; Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Serum Lipids)

41. April 27-30, 1972; Holiday Inn; Notre Dame University; Ames Co; Elkhart, IN

42. Nov 2-5, 1972; Marriott Motor Hotel; Northwestern University Medical School; Chicago, IL (Clinical Pathology of Respiratory Diseases)

43. May 3-5, 1973; Hawaiian Village Motel; St Joseph’s Hospital; University of South Florida College of Medicine; Tampa, FL

44. Nov 2-4, 1973; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Cancer)

45. March 7-10, 1974; La Jolla Village Inn; Scripps Foundation; University of California Medical School; La Jolla, CA

46. Nov 8-10, 1974; Bellevue-Stratford Hotel; Thomas Jefferson Medical College; Philadelphia, PA (Laboratory Diagnosis of Skeletal, Muscular, and Neurological Disorders)

47. May 2-4, 1975; Governors Inn; University of North Carolina Medical School; Chapel Hill, NC

48. Nov 7-9, 1975; Bellevue-Stratford Hotel; Thomas Jefferson Medical School; Philadelphia, PA (Laboratory Diagnosis and Monitoring of Disorders Caused by Drugs and Toxic Agents)

49. April 21-25, 1976; Hyatt Hotel; University of Puerto Rico Medical School; San Juan, PR

50. Nov 5-7, 1976; Shoreham Hotel, Washington, DC (Clinical Enzymology)

51. March 2-5, 1977; Congress Centre, Monte Carlo, Monaco (International Symposium on Clinical Chemistry and Chemical Toxicology of Metals)

52. April 28-May 1, 1977; Christopher Inn; Battelle Columbus Labs; Ohio State University School of Medicine; Columbus, OH

53. Nov 11-13, 1977; Drake Hotel, Northwestern University Medical School; Chicago, IL (Proteins and Proteinopathies)

54. May 4-7, 1978; Fairmont Hotel; University of California Medical School; San Francisco, CA

55. May 22-24, 1978; Caledonian Hotel; Falconbridge Nikkelwerk; Kristiansand, Norway (Kristiansand Conference on Nickel Toxicology)

56. Nov 3-5, 1978; Shoreham Hotel, Washington, DC (Clinical Pathology of Cancer of the Endocrine Glands and Target Organs)

57. May 3-6, 1979; Mills-Hyatt House; Medical University of South Carolina; Charleston, SC

58. Oct. 11-14, 1979; Benjamin Franklin Hotel; Jefferson Medical College; Philadelphia, PA (Biochemical Hematology)

59. May 8-11, 1980; Colonnade Hotel; Harvard Medical School; Boston, MA

60. Sept 3-5, 1980; Dragon Hotel; University College of Swansea; Swansea, Wales, United Kingdom (Swansea Conference on Nickel Toxicology)

61. Oct 31-Nov. 2, 1980; Drake Hotel, Chicago, IL (Laboratory Diagnosis and Monitoring of Disorders of the Kidney)

62. May 7-10, 1981; Bay Harbor Inn; St Joseph’s Hospital; University of South Florida College of Medicine; Tampa, FL

63. Oct 29-Nov 1, 1981; Barclay Hotel, Philadelphia, PA (Diagnosis of Disorders of the Fetus, Newborn, and Infant)

64. May 6-9, 1982; Sheraton-Miramar Hotel; UCLA Medical School; Beckman Instruments, Inc; Santa Monica, CA

65. June 17-20, 1982; Hotel Vier Jahreszeiten, Munich, Federal Republic of Germany (International Conference on Human Tumor Markers)

66. Nov 11-13, 1982; Drake Hotel, Chicago, IL (Laboratory Diagnosis and Monitoring of Cancer)

67. May 12-15, 1983; Boar’s Head Inn; University of Virginia Medical Center; Charlottesville, VA

68. July 19-22, 1983; Sheraton Centre, Montreal, Canada (Second International Conference on Clinical Chemistry and Chemical Toxicology of Metals)

69. Nov 10-13, 1983; Shoreham Hotel, Washington, DC (Clinical Pathology of Liver and Biliary Tract)

70. Feb 20-22, 1984; Hilton Hotel, Vienna, Austria (Second International Congress on Human Tumor Markers)

71. May 3-6, 1984; Hilton Hotel; University of South Alabama Medical School; Mobile, AL

72. Sept 4-7, 1984; PLM-St Jacques Hotel; Société Le Nickel; Paris, France (Nickel Metabolism and Toxicology)

73. Nov 15-18, 1984; Barclay Hotel, Philadelphia, PA (Clinical Pathology of the Reproductive Systems)

74. May 9-12, 1985; Sheraton-Islander Hotel; Brown University Medical School; Newport, RI

75. Oct 9-13, 1985; Galt House Hotel; Audubon Hospital; Louisville, KY (Diagnosis of Cardiovascular Disorders)

76. April 23-26, 1986; Ischia, Italy (Third International Conference on Human Tumor Markers)

77. May 15-18, 1986; Excelsior Hotel; University of Arkansas Medical School; Little Rock, AR

78. July 28-Aug 1, 1986; University of Occupational and Environmental Health, Kitakyushu, Japan (Third International Conference on Clinical Chemistry and Chemical Toxicology of Metals)

79. Nov 13-16, 1986; Colony Square Hotel; Emory University School of Medicine; Atlanta, GA (Nucleic Acid Probes and Monoclonal Antibodies in Human Disease)

80. May 14-17, 1987; The Charleston Place Hotel; Medical University of South Carolina; Charleston, SC

81. Aug 17-21, 1987; Odense University, Denmark (Symposium on Trace Elements in Human Health & Disease)

82. Aug 25-28, 1987; Omni Park Hotel, New York, NY (Fourth International Conference on Human Tumor Markers)

83. Nov 12-15, 1987; Lincoln Hotel, Tampa, FL (Applied Seminar on Analytical and Clinical Toxicology)

84. May 12-15, 1988; Newporter Resort; UCLA Medical School; Beckman Instruments; Newport Beach, CA

85. May 29-June 3, 1988; Brioni Hotel, Brioni, Yugoslavia (Symposium on Drugs in Competitive Athletics)

86. Sept 5-9, 1988; Hanasaari Centre, Helsinki, Finland (Fourth International Conference on the Metabolism and Toxicology of Nickel)

87. Sept 19-23, 1988; Stockholm, Sweden (Fifth International Conference on Human Tumor Markers)

88. Nov 10-13, 1988; Parkview-Hilton Hotel, Hartford, CT; University of Connecticut Medical School, Farmington, CT (Applied Seminar on Hematology)

89. May 11-14, 1989; Omni Hotel; University of Virginia Medical School; Charlottesville, VA

90. May 23-26, 1989; Miyako Hotel, Tokyo, Japan (Sixth International Conference on Human Tumor Markers)

91. November 16-19, 1989; Hershey Hotel, Philadelphia, PA (Applied Seminar on Laboratory Diagnosis of Liver Diseases)

92. May 10-13, 1990; Meridien Hotel; University of British Columbia Faculty of Medicine; Vancouver, BC, Canada

93. June 5-8, 1990; Hanasaari Centre, Espoo, Helsinki, Finland (Fourth International Symposium on Trace Elements in Health and Disease)

94. September 10-14, 1990; Hotel Rus, Kiev, Russia (Seventh International Conference on Human Tumor Markers)

95. November 7-11, 1990; Clarion Hotel; University of Cincinnati Medical School; Cincinnati, OH (The Laboratory Diagnosis of Disorders of the Fetus, Newborn, and Early Childhood)

96. May 8-12, 1991; Red Lion Hotel; University of Utah Medical School; Salt Lake City, UT

97. September 9-12,1991; Triaena Congress Centre, Athens, Greece (International Congress on Immunoenzymatic Techniques)

98. November 14-17, 1991; Omni Hotel, Jacksonville, FL (Six Major Advances in Laboratory Diagnosis and Clinical Applications)

99. May 13-17, 1992; Sheraton University Inn; Medical School of the State University of New York; Syracuse, NY

100. Sept 6-10, 1992; Vienna, Austria (Ninth International Conference on Human Tumor Markers)

101. Nov 11-15, 1992; Red Lion Resort; Sansum Medical Foundation; Santa Barbara, CA (Laboratory Diagnosis of Metabolic Disorders, Emphasizing Diabetes Mellitus)

102. May 12-16, 1993; Newport Islander Doubletree Hotel; Brown University Medical School; Newport, RI

103. Sept 6-10, 1993; Bonn, Germany (Tenth International Conference on Human Tumor Markers)

104. Nov 3-7, 1993; Hilton Hotel; Medical College of Ohio; Toledo, OH (Advances in the Laboratory Diagnosis of Cancer)

105. May 11-15, 1994; Lodge Alley Inn; Medical University of South Carolina; Charleston, SC

106. Nov 16-20, 1994; Holiday Inn Crowne Plaza; University of South Florida College of Medicine; Tampa, FL (Clinical Science of Ageing)

107. May 10-14, 1995; Houston Plaza Hilton Hotel; MD Anderson Cancer Center; University of Texas School of Medicine; Houston, TX

108. June 11-14, 1995; New York Hilton, New York, NY (Twelfth International Conference on Human Tumor Markers)

109. July 10-13, 1995; University of British Columbia, Vancouver, Canada (Fifth International Symposium on Toxicology & Clinical Chemistry of Metals)

110. Oct 25-29 1996; Holiday Inn Crowne Plaza, Redondo Beach, CA (Immunologic Techniques for Diagnosis, Transplantation, and Therapy)

111. May 1-5, 1996; Carolina Inn; University of North Carolina Medical School; Chapel Hill, NC

112. June 16-19, 1996; Shangri-La Hotel, Singapore (Thirteenth International Conference on Human Tumor Markers)

113. Oct 30 - Nov 3 1996; Seelbach Hotel; University of Louisville Medical School; Louisville, KY (Neurologic and Psychiatric Diseases: Molecular Basis and Diagnostic Approaches)

114. May 7-11, 1997; University Park Hotel; University of Utah School of Medicine; ARUP Laboratories; Salt Lake City, UT

115. November 5-9, 1997; Emory Conference Hotel; Emory University School of Medicine; Atlanta, GA (Laboratory Diagnosis of Infectious Diseases)

116. April 29 - May 3, 1998; Biltmore Hotel; Brown University School of Medicine; Providence, RI

117. October 21-23, 1998; Doubletree Hotel; Jefferson Medical College; Philadelphia, PA (Clinical Science in the New Millennium)

118. October 5-9, 1999; Fawcett Center Hotel; Ohio State University Medical School; Columbus, OH

119. Nov 3-7, 1999; Radisson Hotel La Jolla; University of California at San Diego; Scripps Research Institute; La Jolla, CA (Molecular and Clinical Immunology and Immunopathology)

120. May 17-20, 2000; Partridge Inn; Medical College of Georgia; Augusta, GA Hemoglobinopathies)

121. May 9-12, 2001; The Carolina Inn; The University of North Carolina School of Medicine; Chapel Hill, NC (Applications of Molecular Biology in Laboratory Diagnosis)

122. May 8-11, 2002; Hotel Monaco; The University of Utah School of Medicine; ARUP Laboratories, Salt Lake City, UT (Sports Medicine, Fitness Training, and Related Topics)

123. May 7-11, 2003; TradeWinds Resort, University of South Florida College of Medicine; University of Tampa, St Petersburg, FL (Metabolic Diseases)

124. May 12-16, 2004; Warwick Hotel; University of Texas College of Medicine; The M.D. Anderson Cancer Center; Houston, TX (Infectious Diseases and Pulmonary Pathology; Informatics in Pathology and Laboratory Medicine)

125. May 11-15, 2005; Somerset Inn; William Beaumont Hospital, Troy and Royal Oak, MI (Diagnostic Applications of Molecular Biology)

126. May 17-21, 2006; Amelia Island Plantation Resort and University of Florida Medical School, Amelia Island (Diseases of the Reproductive Organs; Prevention of Medical Errors)

127. May 16-20, 2007; Hershey Lodge Conference Center, Penn State University Medical School, Geisinger Medical Center, Hershey and Danville, PA (Workshop on Proteomics in Cancer Therapy)

128. May 14-18, 2008; Marina del Mar Hotel and UCLA Medical School, Los Angeles, CA (Symposium on Solid Organ Transplantation)

129. May 13-17 2009; Embassy Suites Hotel; University of South Florida College of Medicine and the University of Tampa, Tampa, FL

130. May 12-16, 2010; St Anthony Hotel; University of Texas Health Science Center, San Antonio, TX (Transfusion Medicine)

131. May 18-22, 2011; Seelbach Hilton Hotel; University of Louisville School of Medicine; Louisville KY (Personalized Medicine and Genomics)

132. May 23-27, 2012; Renaissance Mobile Riverview Plaza Hotel; University of South Alabama School of Medicine; Mobile, AL (Advances in Pathology for Personalized Medicine)

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