Annual Meeting
The 129th Meeting of the Association of Clinical Scientists will be held in Tampa, Florida, from Wednesday, 13 May, to Sunday, 17 May 2009. The headquarters will be the recently constructed Embassy Suites TampaDowntown Convention Center Hotel, located 7 miles from Tampa International Airport. The meeting will be hosted by the University of Tampa and the University of South Florida College of Medicine. Drs. Joseph Laurino and Donald Cannon, Co-Chairs of the Program Committee, cordially invite you to participate in this outstanding conference.
General Schedule
The meeting registration desk will be open and committee meetings will be held at the Embassy Suites Hotel on Wednesday afternoon and evening. Scientific sessions will be held at the hotel on Thursday and Saturday. The Friday morning session will be at the University of Tampa and will include workshops on liquid chromatography-mass spectrometry, inductively coupled plasma-atomic emission spectrometry, and instrumental advances in molecular diagnostics.
Scientific Program
The scientific program, entitled The Frontiers of Clinical Science, will emphasize genetic and environmental causes of disease. The program will begin with the Claude P. Brown Memorial Lecture on “Frontiers of Ovarian Cancer,” presented by Santo V. Nicosia, Chairman of the Department of Pathology and Cell Biology at the University of South Florida.
Platform sessions of research papers will be devoted to Cell and Tissue Pathology, Clinical Biochemistry and Biotechnology, Molecular Biology and Genetics, Clinical Immunology and Microbiology, Hematology and Transfusion Medicine, Therapeutics and Toxicology, Clinical Informatics, and Clinical Science in Practice. The topics of the lectures are:
Wednesday, 13 May (Embassy Suites Hotel)
2:00 pm—Meeting registration desk opens
Thursday, 14 May (Embassy Suites Hotel)
Session A—Frontiers of Clinical Science
8:00 am—Welcome. Vincent A. DeBari, President of the Association; Joseph P. Laurino and Donald J. Cannon, Co-chairs of the
Program Committee
8:05 am—[1] Claude P. Brown Memorial Lecture: Frontiers of ovarian cancer. Santo V. Nicosia, Tampa, FL
9:00 am—[2] Frontiers of research on Alzheimer’s disease. Huntington Potter, Tampa, FL
9:30 am—[3] Signal transduction pathways: A goldmine of anticancer drug targets. Said M. Sebti, Tampa, FL
10:00 am—[4] Teratogenic causes for malformations. Enid Gilbert-Barness, Tampa, FL
10:30 am—Refreshments
Session B—Frontiers of Clinical Science
10:45 am—[5] Geriatric oncology: Integrating biologic variability into clinical research. Martine Extermann, Tampa, FL
11:15 am—[6] Implementation of advanced molecular diagnostics at the James A. Haley Veterans Hospital. Stephen Mastorides,
Tampa, FL
11:45 am—[7] Atypical teratoid/rhabdoid tumor: Morphoproteomics defines its biology and exposes therapeutic targets. Robert E.
Brown et al, Houston, TX
Noon—[8] Overexpression of cancer stem cell markers in fibrolamellar hepatocellular carcinoma. Maryam J. Zenali et al,
Houston, TX
12:15 pm—[9] Morphoproteomics defines the NF-kappaB pathway in fibrolamellar hepatocellular carcinoma. Wei Li et al,
Houston, TX
12:30 pm—Luncheon sponsored by the Section on Clinical Science in Practice
[10] What we forgot to teach in medical school and why it matters. Stephen K. Klasko, Tampa, FL
Session C—Molecular Biology and Genetics
1:45 pm—[11] Dysfunctional regulation of extracellular matrix assembly: Transgenic mice as a model of classic Ehlers-Danlos
syndrome. David E. Birk, Tampa, FL
2:15 pm—[12] A good ending makes a good beginning: The telomere theory of reproductive aging. David L. Keefe, Tampa, FL
2:45 pm—[13] Congenital hepatorenal fibrocystic syndromes: Advances in molecular pathology and genetics. Consolato Sergi,
Edmonton, Canada
3:15 pm—Refreshments
Session D—Oncology and Immunology
3:30 pm—[14] Promises and challenges in cancer immunotherapy. Dimitry I. Gabrilovich, Tampa, FL
4:00 pm—[15] Overview on the evolution of the innate and adaptive immune systems culminating in adoptive immune
lymphocyte therapy. Joseph G. Sinkovics, Tampa, FL
4:30 pm—[16] Myeloproliferative neoplasms: Role of JAK2 mutations. John Lazarchick, Charleston, SC
5:00 pm—[17] Morphoproteomics of multiple signaling pathways in anaplastic thyroid carcinoma. Jing Liu & Robert E. Brown,
Houston, TX
5:15 pm—[18] Modulation of survival and death pathways by sanguinarine in neuroblastoma cells. Priya Weerasinghe et al,
Houston, TX
5:30 pm—General discussion
5:45 pm—Adjournment
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Friday, 15 May (University of Tampa) (Bus leaves hotel at 7:45 am.)
Session E—Clinical Biochemistry and Biotechnology
8:15 am—[19] New trends in liquid chromatographytandem mass spectrometry. Joseph P. Laurino, Tampa, FL
8:45 am—20] A chemistry analyzer is much the same as any other chemistry analyzer, or is it? Clive R. Hamlin, Cleveland, OH
9:00 am—[21] Determination of urinary myo-inositol on an automated chemistry analyzer. Zak K. Shihabi et al, Winston-Salem,
NC.
9:15 am—[22] Using an automated camera system to rapidly inspect for mislabeled specimens. Charles D. Hawker, Salt Lake City,
UT
9:30 am—[23] Minor metabolic products of opiate metabolism: potential for misinterpretation of urine drug testing results.
Roger L. Bertholf & Gary M. Reisfield, Jacksonville, FL
9:45 am—[24] Estimated average glucose: Why? Frederick L. Kiechle, Hollywood, FL
10:00 am—[25] Improving detection in capillary electrophoresis: Example of serum mycophenolic acid. Zak K. Shihabi, Winston-
Salem, NC
10:15 am—Refreshments
Session F—Workshops on Clinical Biochemistry and Biotechnology
10:30 am—(Three groups of participants will rotate through three 30-minute workshops.)
[26] Liquid chromatographytandem mass spectrometry. Scott Allen, Tampa, FL
[27] Inductively coupled plasmaatomic emission spectroscopy. Joseph P. Laurino, Tampa, FL
[28] Instrumental advances in molecular diagnostics. Maura Pieretti, Clearwater, FL
Noon—Bus returns to Hotel
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Saturday, 16 May (Embassy Suites Hotel) (Sessions G & H are concurrent with Sessions I & J.)
Session G—Cell and Tissue Pathology
8:00 am—[29] Surgical Pathology Slide Tutorial on Cancers of the Colon and Breast. Domenico Coppola & Geza Acs, with case
presentations by pathology residents (Evita Henderson-Jackson, Rahel Mathew, Masoumeh Ghayouri), Tampa, FL
9:15 am—[30] Integration of histology and molecular biology in the therapeutic planning for colon cancer. Domenico Coppola,
Tampa, FL
9:45 am—[31] Constitutively active erythropoietin receptors in the growth of human cancer. Geza Acs, Tampa, FL
10:15 am—Refreshments
Session H—Cell and Tissue Pathology
10:30 am—[32] Granulomatous prostatitis secondary to M. tuberculosis complex. Frank M. Taylor, III, et al, Plant City, FL
10:45 am—[33] Iron in neurodegeneration. Joseph C. Parker, Jr., Louisville, KY
11:00 am—[34] Papillary tumor of the pineal region: Two unique case studies. Kyle Richard et al, Louisville, KY
11:15 am—[35] Mechanism of brain edema following intracerebral hemorrhage, Jiping Qi, Harbin, China
11:30 am—[36] Collagenous colitis in the pediatric population. Nina Tatevian, Houston, TX
11:45 am—[37] Pulmonary-renal syndrome: IgA nephropathy presenting with renal failure and pulmonary hemorrhage. Ewa
Elenberg, Houston, TX
Noon—[38] The death of the autopsy and its underestimated utility in modern medicine. Gwendolin J. Godfrey & Joseph C.
Parker, Jr., Louisville, KY
12:15 pm—Luncheon recess
Session I—Clinical Informatics and Computer Systems
8:00 am—[39] Virtual cadavers for 21st century medical education and research. Donald Hilbelink, Tampa, FL
8:30 am—[40] Standardization of bioinformatics. Philip Foulis, Tampa, FL
9:00 am—[41] Computer analysis of histologic images. Ulysses Balis, Ann Arbor, MI
9:30 am—[42] Method for analysis of signaling pathways in multiple organ failure. M Sriram Iyengar et al, Houston, TX
9:45 am—[43] Computer monitoring of quality in anatomic pathology. Myra Wilkerson, Danville, PA
10:00 am—Refreshments
Session J—Clinical Science in Practice
10:15 am—[44] Personalized medicine will be the future. Pai C. Kao, Rochester, MN
10:30 am—[45] Plasma BNP as a biochemical marker for patent ductus arteriosus in pre-term neonates. Vaneet K. Kalra, South
Orange, NJ
10:45 am—[46 Association of D-dimer levels with clinical outcomes in patients presenting with acute pulmonary embolism.
Maria Alfakir et al, South Orange, NJ
Session K—Therapeutics and Toxicology
11:00 am—[47] Poloxamer 188 prolongs survival of hypotensive resuscitation and decreases vital tissue injury after full
resuscitation. Robert Hunter et al, Houston, TX
11:15 am—[48] Unique properties of aluminum maltolate in experimental studies of neurodegeneration. John Savory,
Charlottesville, VA
11:30 am—[49] Anti-tumor effect of a compound extracted from Pteris semipinnata L in mouse models of liver and lung tumors.
George C. Chen et al, Hong Kong, China
11:45 am—[50] Mercury in the environment. Ernest M. Walker, Jr., Huntington, WV
Noon—[51] Deferasirox and iron removal in the iron overloaded gerbil model. Rabaa M. Al-Rousan et al, Huntington, WV, and
Tampa, FL
12:15 am—Luncheon recess. Luncheon sponsored by the Sections on Therapeutics & Toxicology and Clinical Biochemistry & Biotechnology
12:15 pm—[52] Overview of iron metabolism and hemochromatosis. Donald Cannon, Tampa, FL
Session K—Hematology and Transfusion Medicine
1:30 pm—[53] HLA sequence-based typing. Kaaron Benson, Tampa, FL
2:00 pm—[54] Hereditary thrombophilia and the molecular pathogenesis of Factor V Leiden. M. Kent Froberg, Duluth, MN
2:30 pm—[55] Feto-maternal hemorrhage detection techniques. Jonathan S. Krauss, Augusta, GA
3:00 pm—Refreshments
Session L—Clinical Microbiology and Immunology
3:15 pm—[56] Dermatopathologic manifestations of biowarfare agents. Michael B. Morgan, Tampa, FL
3:45 pm—[57] Multi-drug resistant Acinetobacter infections in Iraq veterans: The Tampa VA experience. L. Brannon Thomas,
Tampa, FL
4:15 pm—[58] Influenza: Considerations in children and adolescents. Armand Glassman, Charleston, SC
4:30 pm—Business Meeting of the Association. Vincent A. DeBari, President
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Schedule of Events
| Wednesday, May 13, 2009 | ||
|---|---|---|
| 2:00 pm | Meeting registration desk opens | Embassy Suites Hotel |
| 2:30 pm | Educational Accreditation Committee meeting | |
| 3:30 pm | Executive Committee meeting | |
| 5:00 pm | Editorial Board meeting | |
| 7:45 pm | Executive Committee meeting with Past-Presidents and Committee Chairs | |
| Thursday, May 14, 2009 | ||
| 8:00am—5:45pm | Scientific program sessions | Embassy Suites Hotel |
| 6:30 pm | Pool-side Caribbean buffet supper | |
| 7:30 pm | Musicale rehearsal | |
| Friday, May 15, 2009 | ||
| 7:45 am | Bus leaves hotel for University of Tampa | |
| 8:15 am—12:00 pm | Scientific program sessions | University of Tampa |
| 12:00 pm | Bus returns to Hotel | |
| 1:45 pm | Bus excursion: A special tour of Tampa for participants and accompanying persons (Bus will return to hotel by 5:30 pm.) | |
| 6:30 pm | Annual Reception and Banquet | Embassy Suites Hotel |
| Toastmaster: Vincent A. DeBari, East Orange, NJ | ||
| Young Clinical Scientist Award: Gillian A. Franklin, Fort Worth, TX | ||
| Diploma of Honor: Jonathan S. Krauss, Augusta, GA | ||
| Clinical Scientist of the Year Award: Steven I. Hajdu, Los Angeles, CA | ||
| Banquet address: "The Florida Dream." | Gary Mormino, Tampa, FL | |
| Saturday, May 16, 2009 | ||
| 8:00 am—4:30 pm | Scientific program sessions |
Embassy Suites Hotel |
| 4:30 pm | Business Meeting of the Association | Vincent A. DeBari, President |
| 7:30 pm | Musicale and Art Show. Organized by Bernard Gondos, Chair of the Committee on Music and Fine Arts | |
Continuing Education (CME and CE)
Accreditation. This activity was planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the College of American Pathologists (CAP) and the Association of Clinical Scientists. The College of American Pathologists is accredited by the ACCME to provide continuing medical education for physicians.
Continuing Medical Education Designation (CME). The College of American Pathologists designates this educational activity for a maximum of 20.25 AMA PRA Category 1 creditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Continuing Education (CE) for Non-physicians Designation. The College of American Pathologists designates this educational activity for a maximum of 20.25 credit hours of continuing education. Participants should only claim credit hours commensurate with the extent of their participation in the activity.
ASCP Statement. This activity is acceptable to meet the continuing education requirements for the ASCP Board of Registry Certification Maintenance Program.
California and Florida Statement. This activity is approved for continuing education credit in California and Florida. Florida non-physicians must provide their license number.
Disclaimer. The content of this CME activity does not necessarily reflect the view or policies of the College of American Pathologists.
Educational Goals. The overall goals of the meeting are to enable the registrants to:
(a) Interpret, discuss, appraise, and apply in the clinical arena the recent advances in laboratory techniques for clinical diagnosis and the frontiers of knowledge about clinical science, including clinical chemistry, immunology, microbiology, hematology, blood banking, toxicology, cell and tissue pathology, informatics, molecular biology, and biotechnology.
(b) Survey the frontiers of research in clinical science, emphasizing important advances in oncology, neurology, teratology, instrumental analysis, and internal medicine.
(c) Analyze the molecular circuitry of cancer cells by examining the expression patterns of specific proteins using immunohistochemical techniques, and apply this information to predict the therapeutic responses of individual tumors to modulators of gene expression.
(d) Become acquainted with the clinical scientists at the University of South Florida College of Medicine and the University of Tampa and appraise their impact on the quality of medical care and clinical science in the USA.
Educational Needs Identified. Specific educational needs of the target audience include:
(a) methods for molecular diagnostics and morphoproteomic profiling of cancers,
(b) instrumental techniques for analytic toxicology and their clinical applications, and
(c) clinical informatics and computer systems for laboratory medicine and quality assurance.
Professional Practice Gaps. Three professional practice gaps are the primary focus of this program:
(a) disparity between the state-of-the-art in cancer morphoproteomics and the availability of immunohistochemical profiling of the morphoproteomic patterns of each cancer patient’s tumor, to guide individual selection of optimal cancer therapy;
(b) disparity between the state-of-the-art analytical instrumentation (eg, inductively coupled plasma atomic emission spectrometry, liquid chromatography-tandem mass spectrometry, molecular diagnostics analyzers) and the utilization of these advanced techniques for clinical diagnosis; and
(c) disparity between the state-of-the-art computer programs for bioinformatics and the application of these programs in clinical teaching, laboratory diagnosis, and quality assurance.
General Educational Objectives. After the meeting, participants should be able to:
(a) Discuss knowledgeably the specific clinical advances and research findings that were presented,
(b) Decide which advances and findings have applications in their daily work as clinical scientists, and
(c) Adjust their professional activities and research programs to the prevailing currents of clinical science and medical practice.
At the conclusion of this activity, participants should be able to fulfill the specific learning objectives of each presentation that they attended. The specific learning objectives are printed at the end of each abstract in the Program and Abstracts book.
Evidence-based Recommendations. The College of American Pathologists and the Association of Clinical Scientists are dedicated to promoting improvements on quality in healthcare and not a specific proprietary business interest or a commercial interest. Therefore the College of American Pathologists and the Association of Clinical Scientists expect all planners/faculty/authors of these educational activities to make all recommendations and/or planning criteria involving clinical medicine to be based on evidence that is accepted within the profession of medicine as adequate justification for these indications and contraindications in the care of patients.
Methods and Evaluation. This program will use lectures, case discussions, laboratory workshops, a tutorial session, and question-and-answer periods as the primary educational methods. A course evaluation form will provide participants with the opportunity to assess each session and speaker, to identify future educational needs, and to comment on any perceived commercial bias in the presentations.
Policies and Notices. The faculty members are required to disclose any significant financial or other relationships with commercial companies whose products may be discussed. The faculty must disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Audiotaping and videotaping are prohibited.
Registration
The regular registration fee is $395. Junior members, emeritus members, and non-member residents or post-doctoral fellows may pay a reduced fee ($295). The registration fee includes one ticket to the reception and banquet on Friday evening. Tickets for the luncheons of scientific sections cost $25. Admission to the musicale and art show on Saturday evening is free. The meeting registration form may be downloaded (pdf form) and sent to the Secretary-Treasurer by fax or regular mail.
Hotel Accommodations
The new Embassy SuitesTampa Downtown Convention Center Hotel has splendid guest rooms and conference facilities. All accommodations include a spacious two-room suite, cooked-to-order breakfast, and nightly Manager’s Reception. The amenities include a beautiful outdoor lap-pool and sun deck and a state-of-the-art fitness center. The hotel’s address is 513 South Florida Avenue, Tampa, FL 33602. The hotel’s website is www.Tampadowntown.embassysuites.com. The convention rate for our meeting will be $189/room (single or double). The number of available rooms is limited, so you should make your reservations early by calling the hotel at (813) 769 8300, or by sending a fax to (813) 769 8307. Please specify that you will attend the Association’s meeting. The cut-off date for reservations at our special convention rate is 13 April 2009.
Transportation
Tampa International Airport, a destination for all major airlines, is only a 12-minute drive to the Embassy Suites-Tampa Downtown Convention Center Hotel. The taxi fare is approximately $25. Shuttle bus service by Blue One Transportation (813 927 3602) costs $13 for one person or $11 for two or more persons.